A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Previous index(es): Acetamides (1971-1974)
Semantic type(s): Organic Chemical; Indicator, Reagent, or Diagnostic Aid; Hazardous or Poisonous Substance
MeSH record created: 11/11/1974
MeSH record revised: 05/07/2006